Compounded semaglutide with B12

What the medication is used for

Compounded semaglutide with B12 is a compounded medication. Compounded medications are not approved by the FDA, and the FDA does not review them for safety, effectiveness, or quality as compounded products.

A licensed provider may consider compounded semaglutide with B12 for weight management, based on your health history, current medications, allergies, location, and other clinical information. This page does not describe an FDA-approved product.

Who may not be able to use it

A provider may determine that compounded semaglutide with B12 is not appropriate if you or a family member has a personal or family history of medullary thyroid carcinoma, or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Animal studies of this class of medication have shown thyroid C-cell tumors, and this risk in humans has not been ruled out.

A provider may also determine it is not appropriate if you have a history of pancreatitis, severe gastrointestinal disease, a known serious allergy to any ingredient, or if you are pregnant, trying to conceive, or breastfeeding.

Important warnings and precautions

Compounded semaglutide with B12 carries warnings that a provider will review with you before prescribing, including a boxed warning about the risk of thyroid C-cell tumors seen in animal studies with this class of medication, and the related contraindication for people with a personal or family history of medullary thyroid carcinoma or MEN 2.

Other warnings include inflammation of the pancreas (pancreatitis), gallbladder problems, low blood sugar (which is more likely if you also take insulin or a sulfonylurea), kidney problems related to dehydration, vision changes, allergic reactions, gastroparesis and severe slowing of stomach emptying, and mood changes including depression or thoughts of self-harm.

Tell any surgeon, anesthetist, or endoscopist that you use this medication, because it slows gastric emptying and can affect procedures that require an empty stomach.

See Important Safety Information at /safety-information for the full safety summary that applies across Julora's compounded medications.

Common side effects

Common side effects reported with this class of medication include nausea, vomiting, diarrhea, constipation, stomach pain, indigestion, burping, tiredness, headache, dizziness, and injection-site reactions.

Important interactions

This medication can interact with insulin, sulfonylureas, and other medications that lower blood sugar, increasing the risk of low blood sugar. It can also affect how well other oral medications are absorbed because it slows stomach emptying.

Tell your provider about every prescription medication, over-the-counter medication, and supplement you take before starting treatment.

Pregnancy and breastfeeding information

This medication is not for use in pregnancy, while trying to conceive, or while breastfeeding. Tell your provider right away if you become pregnant or are planning a pregnancy.

How the medication is dispensed

Compounded semaglutide with B12 is dispensed by VSDH, a state-licensed compounding pharmacy, after a licensed provider issues a valid prescription. Once prescribed, VSDH prepares your prescription and ships it to the address on your Julora account.

How the medication is stored

Follow the storage and missed-dose instructions on your medication label and in the material VSDH sends with your prescription, and ask your provider or the pharmacy if anything is unclear.

What to do if a dose is missed

Follow the storage and missed-dose instructions on your medication label and in the material VSDH sends with your prescription, and ask your provider or the pharmacy if anything is unclear.

How to contact the pharmacy

Contact the pharmacy using the contact details supplied with your prescription for questions about your medication label, delivery, storage, or the product you received.

How to report a side effect

You can report a side effect through Julora's secure clinical messaging channel, directly to VSDH, the dispensing pharmacy, or to the FDA MedWatch program at 1-800-FDA-1088 or fda.gov/medwatch.

Price and renewal terms

Compounded Semaglutide + B12, Starter (4 weeks): $179 for the first 4 weeks, then $229 every 4 weeks. Compounded Semaglutide + B12, Maintenance (4 weeks): $219 for the first 4 weeks, then $269 every 4 weeks. Compounded Semaglutide + B12, Maintenance (12 weeks): $719 every 12 weeks. Your card is saved securely when you order and is only charged after a licensed provider reviews your medical intake and approves treatment. A provider typically completes this review within 24 to 48 hours. If the provider does not approve treatment for you, you are not charged and nothing ships. Completing an order is not a prescription and does not guarantee one. You can cancel at any time in your account or by emailing support@getjulorahealth.com before your next billing date. Medication that has already shipped cannot be returned.

State and service availability

Availability depends on the specific service, your location, the provider's license, and pharmacy licensing in your state. Use the availability checker at /check-availability to see what may be available to you.